February 8th 2019

In 194 head-to-head RCTs, agomelatine, amitriptyline, escitalopram, mirtazapine, paroxetine, venlafaxine and vortioxetine were more effective than other antidepressants, whereas fluoxetine, fluvoxamine, reboxetine, and trazodone were the least effective. Agomelatine, citalopram, escitalopram, fluoxetine, sertraline and vortioxetine were better tolerated than others. Amitriptyline, clomipramine, duloxetine, fluvoxamine, reboxetine, trazodone and venlafaxine were associated…

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January 29th 2018

This NICE guideline provides recommendations on symptom management (pain, breathlessness, nausea and vomiting, anxiety, delirium, agitation and noisy respiratory secretions) and maintaining hydration in adult patients receiving palliative care during the last days of life (two to three). The recommendations included in this guideline include: Recognising when people are entering…

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January 29th 2018

Palliative care can provide great comfort to patients suffering from a terminal illness, and also their families. The World Health Organisation (WHO) defines palliative care as “an approach that improves the quality of life of patients and their families facing the problem associated with life-threatening illness, through the prevention and…

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